Matrix metalloproteinase 2 contributes to pancreatic Beta cell injury induced by oxidative stress.

Matrix metalloproteinase 2 contributes to pancreatic Beta cell injury induced by oxidative stress.

To investigate the role of matrix metalloproteinase 2 (MMP2) in pancreatic beta cell injury induced by oxidative stress.Rat pancreatic beta cell line INS-1 cells were treated with advanced glycation end-products (AGE) to induce intracellular oxidative stress. Intracellular MMP2 expression and activi...

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Bibliographic Details
Main Authors: Chongxiao Liu, Xiaoyu Wan, Tingting Ye, Fang Fang, Xueru Chen, Yuanwen Chen, Yan Dong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4198245?pdf=render

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