Hepatitis C Virus and Nonliver Solid Cancers: Is There an Association between HCV and Cancers of the Pancreas, Thyroid, Kidney, Oral Cavity, Breast, Lung, and Gastrointestinal Tract?

Hepatitis C virus (HCV) is known for its oncogenic potential and has been found to be associated with hepatocellular carcinoma (HCC) and non-Hodgkin lymphoma. It has also been postulated that HCV may play a role in the development of other extrahepatic solid tumors of other organs of the body since...

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Main Authors: Saad Qadwai, Tayyaba Rehman, Jonathan Barsa, Zeeshan Solangi, Edward Lebovics
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2017/8349150
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spelling doaj-f9159bf199f547dcad2177ff1c0292bb2020-11-25T02:33:11ZengHindawi LimitedGastroenterology Research and Practice1687-61211687-630X2017-01-01201710.1155/2017/83491508349150Hepatitis C Virus and Nonliver Solid Cancers: Is There an Association between HCV and Cancers of the Pancreas, Thyroid, Kidney, Oral Cavity, Breast, Lung, and Gastrointestinal Tract?Saad Qadwai0Tayyaba Rehman1Jonathan Barsa2Zeeshan Solangi3Edward Lebovics4New York Medical College and Westchester Medical Center, 100 Woods Road, Valhalla, NY 10595, USABristol-Myers Squibb, 5 Research Pkwy, Wallingford, CT 06492, USANew York Medical College and Westchester Medical Center, 100 Woods Road, Valhalla, NY 10595, USANew York Medical College and Westchester Medical Center, 100 Woods Road, Valhalla, NY 10595, USANew York Medical College and Westchester Medical Center, 100 Woods Road, Valhalla, NY 10595, USAHepatitis C virus (HCV) is known for its oncogenic potential and has been found to be associated with hepatocellular carcinoma (HCC) and non-Hodgkin lymphoma. It has also been postulated that HCV may play a role in the development of other extrahepatic solid tumors of other organs of the body since it has been isolated from the vessel wall, kidney, and oral mucosa. In this article, we have reviewed epidemiological studies that have been done to look into the relationship of HCV with nonliver solid cancers of the pancreas, thyroid, renal, oral cavity, breast, and lung and nonpancreatic gastrointestinal cancers. Based on this review, HCV might be associated with an increased risk of renal cell and lung cancers.http://dx.doi.org/10.1155/2017/8349150
collection DOAJ
language English
format Article
sources DOAJ
author Saad Qadwai
Tayyaba Rehman
Jonathan Barsa
Zeeshan Solangi
Edward Lebovics
spellingShingle Saad Qadwai
Tayyaba Rehman
Jonathan Barsa
Zeeshan Solangi
Edward Lebovics
Hepatitis C Virus and Nonliver Solid Cancers: Is There an Association between HCV and Cancers of the Pancreas, Thyroid, Kidney, Oral Cavity, Breast, Lung, and Gastrointestinal Tract?
Gastroenterology Research and Practice
author_facet Saad Qadwai
Tayyaba Rehman
Jonathan Barsa
Zeeshan Solangi
Edward Lebovics
author_sort Saad Qadwai
title Hepatitis C Virus and Nonliver Solid Cancers: Is There an Association between HCV and Cancers of the Pancreas, Thyroid, Kidney, Oral Cavity, Breast, Lung, and Gastrointestinal Tract?
title_short Hepatitis C Virus and Nonliver Solid Cancers: Is There an Association between HCV and Cancers of the Pancreas, Thyroid, Kidney, Oral Cavity, Breast, Lung, and Gastrointestinal Tract?
title_full Hepatitis C Virus and Nonliver Solid Cancers: Is There an Association between HCV and Cancers of the Pancreas, Thyroid, Kidney, Oral Cavity, Breast, Lung, and Gastrointestinal Tract?
title_fullStr Hepatitis C Virus and Nonliver Solid Cancers: Is There an Association between HCV and Cancers of the Pancreas, Thyroid, Kidney, Oral Cavity, Breast, Lung, and Gastrointestinal Tract?
title_full_unstemmed Hepatitis C Virus and Nonliver Solid Cancers: Is There an Association between HCV and Cancers of the Pancreas, Thyroid, Kidney, Oral Cavity, Breast, Lung, and Gastrointestinal Tract?
title_sort hepatitis c virus and nonliver solid cancers: is there an association between hcv and cancers of the pancreas, thyroid, kidney, oral cavity, breast, lung, and gastrointestinal tract?
publisher Hindawi Limited
series Gastroenterology Research and Practice
issn 1687-6121
1687-630X
publishDate 2017-01-01
description Hepatitis C virus (HCV) is known for its oncogenic potential and has been found to be associated with hepatocellular carcinoma (HCC) and non-Hodgkin lymphoma. It has also been postulated that HCV may play a role in the development of other extrahepatic solid tumors of other organs of the body since it has been isolated from the vessel wall, kidney, and oral mucosa. In this article, we have reviewed epidemiological studies that have been done to look into the relationship of HCV with nonliver solid cancers of the pancreas, thyroid, renal, oral cavity, breast, and lung and nonpancreatic gastrointestinal cancers. Based on this review, HCV might be associated with an increased risk of renal cell and lung cancers.
url http://dx.doi.org/10.1155/2017/8349150
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