Analysis of the spatial and dynamical properties of a multiscale model of intestinal crypts
The preliminary analyses on a multiscale model of intestinal crypt dynamics are here presented. The model combines a morphological model, based on the Cellular Potts Model (CPM), and a gene regulatory network model, based on Noisy Random Boolean Networks (NRBNs). Simulations suggest that the stochas...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Open Publishing Association
2013-09-01
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| Series: | Electronic Proceedings in Theoretical Computer Science |
| Online Access: | http://arxiv.org/pdf/1309.7693v1 |
| Summary: | The preliminary analyses on a multiscale model of intestinal crypt dynamics are here presented. The model combines a morphological model, based on the Cellular Potts Model (CPM), and a gene regulatory network model, based on Noisy Random Boolean Networks (NRBNs). Simulations suggest that the stochastic differentiation process is itself sufficient to ensure the general homeostasis in the asymptotic states, as proven by several measures. |
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| ISSN: | 2075-2180 |