Design, synthesis, and biologic evaluation of novel chrysin derivatives as cytotoxic agents and caspase-3/7 activators

Design, synthesis, and biologic evaluation of novel chrysin derivatives as cytotoxic agents and caspase-3/7 activators

Buthina Abdallah Al-Oudat,1 Mohammad Ali Alqudah,2 Suaad Abdallah Audat,3 Qosay Ali Al-Balas,1 Tamam El-Elimat,1 Mohammad Abdelhafeez Hassan,1 Islam Nawaf Frhat,1 Marwah Mohammad Azaizeh2 1Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Jordan University of Science and Tec...

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Bibliographic Details
Main Authors: Al-Oudat BA, Alqudah MA, Audat SA, Al-Balas QA, El-Elimat T, Hassan MA, Frhat IN, Azaizeh MM
Format: Article
Language:English
Published: Dove Medical Press 2019-01-01
Series:Drug Design, Development and Therapy
Subjects:
Chrysin
Design
Synthesis
Cytotoxicity
Caspase 3/7
antiproliferative agents
Online Access:https://www.dovepress.com/design-synthesis-and-biologic-evaluation-of-novel-chrysin-derivatives--peer-reviewed-article-DDDT

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