Cardiac deletion of Smyd2 is dispensable for mouse heart development.

Chromatin modifying enzymes play a critical role in cardiac differentiation. Previously, it has been shown that the targeted deletion of the histone methyltransferase, Smyd1, the founding member of the SET and MYND domain containing (Smyd) family, interferes with cardiomyocyte maturation and proper...

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Main Authors: Florian Diehl, Mark A Brown, Machteld J van Amerongen, Tatyana Novoyatleva, Astrid Wietelmann, June Harriss, Fulvia Ferrazzi, Thomas Böttger, Richard P Harvey, Philip W Tucker, Felix B Engel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20305823/pdf/?tool=EBI

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