Evidences of CTLA-4 and PD-1 Blocking Agents-Induced Cardiotoxicity in Cellular and Preclinical Models

Evidences of CTLA-4 and PD-1 Blocking Agents-Induced Cardiotoxicity in Cellular and Preclinical Models

Background: Several strategies based on immune checkpoint inhibitors (ICIs) have been developed for cancer therapy, opening to advantages in cancer outcomes. However, several ICI-induced side effects have emerged in these patients, especially a rare but clinically significant cardiotoxicity with hig...

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Bibliographic Details
Main Authors: Vincenzo Quagliariello, Margherita Passariello, Domenica Rea, Antonio Barbieri, Martina Iovine, Annamaria Bonelli, Antonietta Caronna, Gerardo Botti, Claudia De Lorenzo, Nicola Maurea
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Journal of Personalized Medicine
Subjects:
cardiotoxicity
nivolumab
ipilimumab
immune checkpoint inhibitors
cardioncology
Online Access:https://www.mdpi.com/2075-4426/10/4/179

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https://www.mdpi.com/2075-4426/10/4/179

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