A Screen for Candidate Targets of Lysine Polyphosphorylation Uncovers a Conserved Network Implicated in Ribosome Biogenesis

Summary: Polyphosphates (polyP) are chains of inorganic phosphates found in all cells. Previous work has implicated these chains in diverse functions, but the mechanism of action is unclear. A recent study reports that polyP can be non-enzymatically and covalently attached to lysine residues on yeas...

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Main Authors: Amanda Bentley-DeSousa, Charlotte Holinier, Houman Moteshareie, Yi-Chieh Tseng, Sam Kajjo, Christine Nwosu, Giuseppe Federico Amodeo, Emma Bondy-Chorney, Yuka Sai, Adam Rudner, Ashkan Golshani, Norman E. Davey, Michael Downey
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718303140