Variations in adrenal hormones in law enforcement servicemen during a mission to local armed conflict

• Main Authors: Roman Victorovich Koubassov, Yury Evlampievich Barachevsky
• Format: Article
• Language: English
• Published: American Journal of Experimental and Clinical Research 2014-09-01
• Series: American Journal of Experimental and Clinical Research
• Subjects: Law enforcement officer, adrenaline, noradrenaline, adrenocorticotropic hormone, cortisol, emergency condition
• Online Access: http://journals.sfu.ca/ajecr/index.php/ajecr/article/view/27
• ISSN: 2330-9237; 2330-9245

<p><span lang="EN-US"><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-weight: bold;" lang="EN-US"><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-weight: bold;" lang="EN-US">In a<strong> </strong>previous study, we reported changes in the adrenocorticotropic hormone (ACTH) and cortisol secretion in blood samples from law enforcement personnel during the mission to local armed conflict region. In the present study, we demonstrate those changes collectively with additional data on changes in t</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'MS Mincho'; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US">he adrenaline</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US"> and</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'MS Mincho'; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US"> noradrenaline in </span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US">the urine samples of the same individuals. The study was conducted on 48 male officers who were deployed to an army conflict teritory for a duration of 4 months</span><span style="color: black; font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'MS Mincho'; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-no-proof: yes;" lang="EN-US">.</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US">At the onset of the</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'MS Mincho'; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US"> mission</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US">, </span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US">there </span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US">was </span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'MS Mincho'; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US">a</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US"> modest</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US">increase</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US">in </span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'MS Mincho'; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US">all hormones </span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US">corresponding </span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'MS Mincho'; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US">to </span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US">the general </span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'MS Mincho'; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US">adaptation syndrome theory. </span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-no-proof: yes;" lang="EN-US">As the mission started, significant increases were observed in the mean levels of the hormonal parameters in both serum and urine at different time points as compared to those before the mission.</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-bidi-font-size: 9.0pt; mso-no-proof: yes;" lang="EN-US"> At first week of deployment, a sharp increase in the secretory activity of medulla and cortical adrenal gland was found and at the termination of the mission a dysfunction of hypophysis-adrenal gland regulation system was identified. These findings might lead to </span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'MS Mincho'; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-no-proof: yes;" lang="EN-US">disturbances</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-no-proof: yes;" lang="EN-US"> in</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'MS Mincho'; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-no-proof: yes;" lang="EN-US"> interhormonal relation</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-no-proof: yes;" lang="EN-US">ships</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'MS Mincho'; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-no-proof: yes;" lang="EN-US"> and</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-no-proof: yes;" lang="EN-US"> cause</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-no-proof: yes;" lang="EN-US">decreased </span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'MS Mincho'; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-no-proof: yes;" lang="EN-US">stress tolerance</span><span style="font-family: 'Times New Roman','serif'; font-size: 10pt; mso-fareast-font-family: 'ＭＳ 明朝'; mso-fareast-theme-font: minor-fareast; mso-ansi-language: EN-US; mso-fareast-language: JA; mso-bidi-language: AR-SA; mso-no-proof: yes;" lang="EN-US"> in the relevant individals</span>.</span></span></p>