Blockade of nociceptin/orphanin FQ signaling facilitates an active copying strategy due to acute and repeated stressful stimuli in mice

Blockade of nociceptin/orphanin FQ signaling facilitates an active copying strategy due to acute and repeated stressful stimuli in mice

The role of stress in the etiology of depression has been largely reported. In this line, exogenous glucocorticoids are employed to mimic the influence of stress on the development of depression. The N/OFQ-NOP receptor system has been implicated in the modulation of stress and emotional behaviors. I...

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Bibliographic Details
Main Authors: Victor A.D. Holanda, Matheus C. Oliveira, Edilson D. Da Silva Junior, Girolamo Calo', Chiara Ruzza, Elaine C. Gavioli
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Neurobiology of Stress
Subjects:
Nociceptin/orphanin FQ
NOP receptor
SB-612111
Dexamethasone
Forced swimming test
Mouse
Online Access:http://www.sciencedirect.com/science/article/pii/S235228952030045X

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