Heparin-conjugated collagen as a potent growth factor-localizing and stabilizing scaffold for regenerative medicine

Introduction: Growth factors are crucial bioactive molecules in vitro and in vivo. Among them, basic fibroblast growth factor (bFGF) has been used widely for various applications such as cell culture and regenerative medicine. However, bFGF has extremely poor stability in aqueous solution; thus, it...

Full description

Bibliographic Details
Main Authors: Yasuhiro Ikegami, Hideyuki Mizumachi, Kozue Yoshida, Hiroyuki Ijima
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Regenerative Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S235232042030078X