Reduced cell proliferation and promotion of apoptosis by Leu5AMD in osteosarcoma cells

Leu5AMD is an actinomycin D (AMD) analog obtained by replacing both N-methylvalines present in AMD with N-methylleucines. The potential of Leu5AMD for the treatment of osteosarcoma cells and its mechanism of action are not clearly understood. In this study, we examined the potential use of...

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Bibliographic Details
Main Authors: Wu Xiaofeng, Zhou Zihui
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2017-01-01
Series:Archives of Biological Sciences
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2017/0354-46641700001W.pdf