Effect of Aβ protein on inhibiting proliferation and promoting apoptosis of retinal pigment epithelial cells

Effect of Aβ protein on inhibiting proliferation and promoting apoptosis of retinal pigment epithelial cells

AIM: To identify the effect and regulatory mechanism of amyloid β (Aβ) protein on retinal pigment epithelial (RPE) cells in cell proliferation and apoptosis, and clarify Aβ role in the pathogenesis of age-related macular degeneration (AMD). METHODS: The model of Aβ25-35 protein cytotoxicity in RPE...

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Bibliographic Details
Main Authors: Zi Ye, Shou-Zhi He, Zhao-Hui Li
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2018-06-01
Series:International Journal of Ophthalmology
Subjects:
934
amyloid β protein
retinal pigment epithelial cells
proliferation
apoptosis
receptor for advanced glycation endproducts
nuclear factor-kappaB
age-related macular degeneration
Online Access:http://www.ijo.cn/en_publish/2018/6/20180606.pdf

Internet

http://www.ijo.cn/en_publish/2018/6/20180606.pdf

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