Regulation of vertebrate liver HMG-CoA reductase via reversible modulation of its catalytic activity

Regulation of vertebrate liver HMG-CoA reductase via reversible modulation of its catalytic activity

We have investigated the comparative biochemistry of in vitro regulation of HMG-CoA reductase (EC 1.1.1.34) in microsomal preparations from the livers of nine vertebrates. In all instances, reductase activity was rapidly and profoundly decreased by addition of MgATP. Reductase activities were restor...

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Bibliographic Details
Main Authors:	C F Hunter, V W Rodwell
Format:	Article
Language:	English
Published:	Elsevier 1980-05-01
Series:	Journal of Lipid Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520397893

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