Inducible depletion of adult skeletal muscle stem cells impairs the regeneration of neuromuscular junctions

Inducible depletion of adult skeletal muscle stem cells impairs the regeneration of neuromuscular junctions

Skeletal muscle maintenance depends on motor innervation at neuromuscular junctions (NMJs). Multiple mechanisms contribute to NMJ repair and maintenance; however muscle stem cells (satellite cells, SCs), are deemed to have little impact on these processes. Therefore, the applicability of SC studies...

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Bibliographic Details
Main Authors: Wenxuan Liu, Lan Wei-LaPierre, Alanna Klose, Robert T Dirksen, Joe V Chakkalakal
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-08-01
Series:eLife
Subjects:
synapse
aging
denervation
motor neuron
sarcopenia
satellite cell
Online Access:https://elifesciences.org/articles/09221

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