The Potential of MET Immunoreactivity for Prediction of Lymph Node Metastasis in Early Oral Tongue Squamous Cell Carcinoma

The Potential of MET Immunoreactivity for Prediction of Lymph Node Metastasis in Early Oral Tongue Squamous Cell Carcinoma

ObjectiveMET positivity is independently associated with survival in oral squamous cell carcinoma (OSCC). Since MET is a known orchestrator of invasive tumor growth, we investigated its association with LNM in early oral tongue squamous cell carcinoma (OTSCC). As it is recommended by the NCCN to use...

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Bibliographic Details
Main Authors: Maria J. De Herdt, Berdine van der Steen, Quincy M. van der Toom, Yassine Aaboubout, Stefan M. Willems, Marjan H. Wieringa, Robert J. Baatenburg de Jong, Leendert H. J. Looijenga, Senada Koljenović, Jose A. Hardillo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
MET
occult lymph node metastasis
depth of invasion
oral tongue squamous cell carcinoma
elective neck dissection
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.638048/full

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