Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior

Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior

Summary: Neurexins are key organizer molecules that regulate synaptic function and are implicated in autism and schizophrenia. β-neurexins interact with numerous cell adhesion and receptor molecules, but their neuronal localization remains elusive. Using single-molecule tracking and high-resolution...

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Bibliographic Details
Main Authors: Oliver Klatt, Daniele Repetto, Johannes Brockhaus, Carsten Reissner, Abderazzaq El khallouqi, Astrid Rohlmann, Martin Heine, Markus Missler
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Cell Reports
Subjects:
cell adhesion
synaptic function
neurotransmission
single-particle tracking
protease
electron microscopy
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721006331

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