Peptide Nucleic Acids as miRNA Target Protectors for the Treatment of Cystic Fibrosis

Peptide Nucleic Acids as miRNA Target Protectors for the Treatment of Cystic Fibrosis

Cystic Fibrosis (CF) is one of the most common life shortening conditions in Caucasians. CF is caused by mutations in the CF Transmembrane Conductance Regulator (CFTR) gene which result in reduced or altered CFTR functionality. Several microRNAs (miRNAs) downregulate the expression of CFTR, thus cau...

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Bibliographic Details
Main Authors: Federica Zarrilli, Felice Amato, Carmine Marco Morgillo, Brunella Pinto, Giuliano Santarpia, Nicola Borbone, Stefano D’Errico, Bruno Catalanotti, Gennaro Piccialli, Giuseppe Castaldo, Giorgia Oliviero
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Molecules
Subjects:
cystic fibrosis
CFTR
miRNA
miRNA target protectors
miR-509-3p
peptide nucleic acid
PNA
Online Access:https://www.mdpi.com/1420-3049/22/7/1144

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https://www.mdpi.com/1420-3049/22/7/1144

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