New Insights into Development of Transglutaminase 2 Inhibitors as Pharmaceutical Lead Compounds

Transglutaminase 2 (EC 2.3.2.13; TG2 or TGase 2) plays important roles in the pathogenesis of many diseases, including cancers, neurodegeneration, and inflammatory disorders. Under normal conditions, however, mice lacking TGase 2 exhibit no obvious abnormal phenotype. TGase 2 expression is induced b...

Full description

Bibliographic Details
Main Author: Soo-Youl Kim
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Medical Sciences
Subjects:
Online Access:http://www.mdpi.com/2076-3271/6/4/87

Similar Items