Betacellulin induces increased retinal vascular permeability in mice.

Diabetic maculopathy, the leading cause of vision loss in patients with type 2 diabetes, is characterized by hyper-permeability of retinal blood vessels with subsequent formation of macular edema and hard exudates. The degree of hyperglycemia and duration of diabetes have been suggested to be good p...

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Bibliographic Details
Main Authors: Bela Anand-Apte, Quteba Ebrahem, Alecia Cutler, Eric Farage, Masahiko Sugimoto, Joe Hollyfield, Judah Folkman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2956654?pdf=render