Dose Response of Endotoxin on Hepatocyte and Muscle Mitochondrial Respiration In Vitro
Introduction. Results on mitochondrial dysfunction in sepsis are controversial. We aimed to assess effects of LPS at wide dose and time ranges on hepatocytes and isolated skeletal muscle mitochondria. Methods. Human hepatocellular carcinoma cells (HepG2) were exposed to placebo or LPS (0.1, 1, and 1...
Main Authors: | Victor Jeger, Sebastian Brandt, Francesca Porta, Stephan M. Jakob, Jukka Takala, Siamak Djafarzadeh |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2015-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2015/353074 |
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