Over-expression of HO-1 on mesenchymal stem cells promotes angiogenesis and improves myocardial function in infarcted myocardium

<p>Abstract</p> <p>Heme oxygenase-1 (HO-1) is a stress-inducible enzyme with diverse cytoprotective effects, and reported to have an important role in angiogenesis recently. Here we investigated whether HO-1 transduced by mesenchymal stem cells (MSCs) can induce angiogenic effects...

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Bibliographic Details
Main Authors: Zhang Yan, Ren Xiaofeng, Lin Guosheng, Zeng Bin, Chen Honglei
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/17/1/80