Pulmonary Phaeohyphomycosis Caused by Phaeoacremonium in a Kidney Transplant Recipient: Successful Treatment with Posaconazole

Pulmonary Phaeohyphomycosis Caused by Phaeoacremonium in a Kidney Transplant Recipient: Successful Treatment with Posaconazole

We report a rare case of pulmonary phaeohyphomycosis in a 49-year-old woman 6 years after kidney transplantation. She presented with dyspnea, cough, and fatigue. Her chest CT scan revealed nodular opacities in the right upper lung. A fine needle aspirate biopsy culture yielded Phaeoacremonium and su...

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Main Authors: Saivaralaxmi Monaganti, Carlos A. Q. Santos, Andrea Markwardt, Morgan A. Pence, Daniel C. Brennan
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2014/902818
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spelling doaj-f86b6945231b40b9afe6d55f78324c6b2020-11-24T22:19:35ZengHindawi LimitedCase Reports in Medicine1687-96271687-96352014-01-01201410.1155/2014/902818902818Pulmonary Phaeohyphomycosis Caused by Phaeoacremonium in a Kidney Transplant Recipient: Successful Treatment with PosaconazoleSaivaralaxmi Monaganti0Carlos A. Q. Santos1Andrea Markwardt2Morgan A. Pence3Daniel C. Brennan4The Department of Medicine, Washington University School of Medicine, 660 S. Euclid Avenue, Renal Division/Campus Box 8126, St. Louis, MO 63110, USAThe Department of Medicine, Washington University School of Medicine, 660 S. Euclid Avenue, Renal Division/Campus Box 8126, St. Louis, MO 63110, USABarnes-Jewish Hospital, Center for Outpatient Health, 4901 Forest Park Avenue, 5th Floor, St. Louis, MO 63108, USADepartment of Pathology & Immunology, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8118, St. Louis, MO 63110, USAThe Department of Medicine, Washington University School of Medicine, 660 S. Euclid Avenue, Renal Division/Campus Box 8126, St. Louis, MO 63110, USAWe report a rare case of pulmonary phaeohyphomycosis in a 49-year-old woman 6 years after kidney transplantation. She presented with dyspnea, cough, and fatigue. Her chest CT scan revealed nodular opacities in the right upper lung. A fine needle aspirate biopsy culture yielded Phaeoacremonium and surgical pathology of the biopsy showed chronic inflammation. We successfully treated her with posaconazole and managed drug interactions between posaconazole and tacrolimus. This is the second reported case of biopsy-proven pulmonary infection by Phaeoacremonium in a kidney transplant recipient and successfully treated with posaconazole.http://dx.doi.org/10.1155/2014/902818
collection DOAJ
language English
format Article
sources DOAJ
author Saivaralaxmi Monaganti
Carlos A. Q. Santos
Andrea Markwardt
Morgan A. Pence
Daniel C. Brennan
spellingShingle Saivaralaxmi Monaganti
Carlos A. Q. Santos
Andrea Markwardt
Morgan A. Pence
Daniel C. Brennan
Pulmonary Phaeohyphomycosis Caused by Phaeoacremonium in a Kidney Transplant Recipient: Successful Treatment with Posaconazole
Case Reports in Medicine
author_facet Saivaralaxmi Monaganti
Carlos A. Q. Santos
Andrea Markwardt
Morgan A. Pence
Daniel C. Brennan
author_sort Saivaralaxmi Monaganti
title Pulmonary Phaeohyphomycosis Caused by Phaeoacremonium in a Kidney Transplant Recipient: Successful Treatment with Posaconazole
title_short Pulmonary Phaeohyphomycosis Caused by Phaeoacremonium in a Kidney Transplant Recipient: Successful Treatment with Posaconazole
title_full Pulmonary Phaeohyphomycosis Caused by Phaeoacremonium in a Kidney Transplant Recipient: Successful Treatment with Posaconazole
title_fullStr Pulmonary Phaeohyphomycosis Caused by Phaeoacremonium in a Kidney Transplant Recipient: Successful Treatment with Posaconazole
title_full_unstemmed Pulmonary Phaeohyphomycosis Caused by Phaeoacremonium in a Kidney Transplant Recipient: Successful Treatment with Posaconazole
title_sort pulmonary phaeohyphomycosis caused by phaeoacremonium in a kidney transplant recipient: successful treatment with posaconazole
publisher Hindawi Limited
series Case Reports in Medicine
issn 1687-9627
1687-9635
publishDate 2014-01-01
description We report a rare case of pulmonary phaeohyphomycosis in a 49-year-old woman 6 years after kidney transplantation. She presented with dyspnea, cough, and fatigue. Her chest CT scan revealed nodular opacities in the right upper lung. A fine needle aspirate biopsy culture yielded Phaeoacremonium and surgical pathology of the biopsy showed chronic inflammation. We successfully treated her with posaconazole and managed drug interactions between posaconazole and tacrolimus. This is the second reported case of biopsy-proven pulmonary infection by Phaeoacremonium in a kidney transplant recipient and successfully treated with posaconazole.
url http://dx.doi.org/10.1155/2014/902818
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