Therapeutic effects of metabolic cardioprotector containing L-arginine and inosine in elderly patients with ischemic heart disease

• Main Author: O. A. Vorobjova
• Format: Article
• Language: English
• Published: Zaporozhye State Medical University 2012-08-01
• Series: Patologìâ
• Subjects: endothelial dysfunction; oxidative stress; myocardial ischemia; metabolic cardioprotector
• Online Access: http://pat.zsmu.edu.ua/article/view/16763/14284

Research of an oxidative stress, antioxidant systems, function of vascular endothelium and episodes of myocardial ischemia in 121 elderly patients with IHD (average age 78,75±0,62 years) was performed. Recovery of endothelium-depended vasodilatation, improvement of indexes of nitric oxide metabolism, oxidative stress reduction, decrease of duration and expressiveness of episodes of myocardial ischemia during treatment by metabolic cardioprotector as a part of complex therapy throughout 3 months in these patients were shown.