Pulmonary inflammation-induced alterations in key regulators of mitophagy and mitochondrial biogenesis in murine skeletal muscle

Abstract Background Both mitophagy, a selective mechanism for clearance of mitochondria, and mitochondrial biogenesis are key processes determining mitochondrial content and oxidative capacity of the musculature. Abnormalities in these processes could therefore contribute to deterioration of periphe...

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Bibliographic Details
Main Authors: Pieter A. Leermakers, Alexander H. V. Remels, Ramon C. J. Langen, Annemie M. W. J. Schols, Harry R. Gosker
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Pulmonary Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12890-020-1047-8