The Stochastic Evolution of a Protocell: The Gillespie Algorithm in a Dynamically Varying Volume
We propose an improvement of the Gillespie algorithm allowing us to study the time evolution of an ensemble of chemical reactions occurring in a varying volume, whose growth is directly related to the amount of some specific molecules, belonging to the reactions set. This allows us to study the stoc...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2012-01-01
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| Series: | Computational and Mathematical Methods in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/423627 |
| Summary: | We propose an improvement of the Gillespie
algorithm allowing us to study the time evolution of an ensemble of chemical
reactions occurring in a varying volume, whose growth is directly related to
the amount of some specific molecules, belonging to the reactions set.
This allows us to study the stochastic evolution of a protocell, whose volume
increases because of the production of container molecules. Several protocell
models are considered and compared with the deterministic models. |
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| ISSN: | 1748-670X 1748-6718 |