Gammaherpesvirus infections in equids: a review

Maria Luisa Marenzoni,1 Valentina Stefanetti,1 Maria Luisa Danzetta,1 Peter Joseph Timoney21Department of Veterinary Medicine, University of Perugia, Perugia, Italy; 2Department of Veterinary Science, Maxwell H Gluck Equine Research Center, Lexington, KY, USAAbstract: Although the first equine gamm...

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Main Authors: Marenzoni ML, Stefanetti V, Danzetta ML, Timoney PJ
Format: Article
Language:English
Published: Dove Medical Press 2015-04-01
Series:Veterinary Medicine : Research and Reports
Online Access:http://www.dovepress.com/gammaherpesvirus-infections-in-equids-a-review-peer-reviewed-article-VMRR
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spelling doaj-f848ddfe2823464a9d25acd3d3f079aa2020-11-24T22:57:40ZengDove Medical PressVeterinary Medicine : Research and Reports2230-20342015-04-012015default9110121121Gammaherpesvirus infections in equids: a reviewMarenzoni MLStefanetti VDanzetta MLTimoney PJ Maria Luisa Marenzoni,1 Valentina Stefanetti,1 Maria Luisa Danzetta,1 Peter Joseph Timoney21Department of Veterinary Medicine, University of Perugia, Perugia, Italy; 2Department of Veterinary Science, Maxwell H Gluck Equine Research Center, Lexington, KY, USAAbstract: Although the first equine gammaherpesvirus was identified over 50 years ago, the isolation and characterization of other members of this virus group has been relatively recent. Even so, numerous clinical syndromes have been identified in equid species in association with these viruses. Equid gammaherpesviruses are a genetically heterogeneous viral subfamily, the function of which in host immune modulation and disease pathogenesis has not yet been elucidated. While they share similarities with gammaherpesviruses in humans, the role they play in their relationship with the host is the subject of continued interest and research. Their widespread presence in horses and other equid species provides a considerable challenge in linking them with particular clinical and pathological conditions and in defining their significance from a diagnostic and therapeutic viewpoint. The present review provides an update on the taxonomy, epidemiology, and clinical syndromes, especially respiratory, reported in association with gammaherpesvirus infection in horses, donkeys, and other equid species.Keywords: equid gammaherpesviruses, horses, donkeys, other equid species, equine multinodular pulmonary fibrosishttp://www.dovepress.com/gammaherpesvirus-infections-in-equids-a-review-peer-reviewed-article-VMRR
collection DOAJ
language English
format Article
sources DOAJ
author Marenzoni ML
Stefanetti V
Danzetta ML
Timoney PJ
spellingShingle Marenzoni ML
Stefanetti V
Danzetta ML
Timoney PJ
Gammaherpesvirus infections in equids: a review
Veterinary Medicine : Research and Reports
author_facet Marenzoni ML
Stefanetti V
Danzetta ML
Timoney PJ
author_sort Marenzoni ML
title Gammaherpesvirus infections in equids: a review
title_short Gammaherpesvirus infections in equids: a review
title_full Gammaherpesvirus infections in equids: a review
title_fullStr Gammaherpesvirus infections in equids: a review
title_full_unstemmed Gammaherpesvirus infections in equids: a review
title_sort gammaherpesvirus infections in equids: a review
publisher Dove Medical Press
series Veterinary Medicine : Research and Reports
issn 2230-2034
publishDate 2015-04-01
description Maria Luisa Marenzoni,1 Valentina Stefanetti,1 Maria Luisa Danzetta,1 Peter Joseph Timoney21Department of Veterinary Medicine, University of Perugia, Perugia, Italy; 2Department of Veterinary Science, Maxwell H Gluck Equine Research Center, Lexington, KY, USAAbstract: Although the first equine gammaherpesvirus was identified over 50 years ago, the isolation and characterization of other members of this virus group has been relatively recent. Even so, numerous clinical syndromes have been identified in equid species in association with these viruses. Equid gammaherpesviruses are a genetically heterogeneous viral subfamily, the function of which in host immune modulation and disease pathogenesis has not yet been elucidated. While they share similarities with gammaherpesviruses in humans, the role they play in their relationship with the host is the subject of continued interest and research. Their widespread presence in horses and other equid species provides a considerable challenge in linking them with particular clinical and pathological conditions and in defining their significance from a diagnostic and therapeutic viewpoint. The present review provides an update on the taxonomy, epidemiology, and clinical syndromes, especially respiratory, reported in association with gammaherpesvirus infection in horses, donkeys, and other equid species.Keywords: equid gammaherpesviruses, horses, donkeys, other equid species, equine multinodular pulmonary fibrosis
url http://www.dovepress.com/gammaherpesvirus-infections-in-equids-a-review-peer-reviewed-article-VMRR
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