HYPERALDOSTERONISM – PREVALENCE AND WHERE TO FIND IT

• Main Authors: S. Y. Rybakov, V. O. Shidlovsky, O. V. Shidlovsky
• Format: Article
• Language: Ukrainian
• Published: Ukrmedknyha Publishing House 2017-04-01
• Series: Vіsnik Naukovih Doslіdžen'
• Subjects: симптомокомплекс гіперальдостеронізму; артеріальна гіпертензія; клінічні критерії пошуку.
• Online Access: https://ojs.tdmu.edu.ua/index.php/visnyk-nauk-dos/article/view/7553

Hyperaldosteronism is a complex clinical and pathological hormonal metabolic syndrome, which includes symptoms of vascular tone disorders (hypertension), mineral metabolism, renal and neuromuscular disorders caused by excessive unregulated secretion main mineralocorticoid adrenal hormones – aldosterone and mineralocorticoides close to it. The aim of the study – to review general practitioners, cardiologists, endocrinologists symptom of hyperaldosteronism. Material and Methods. Analysis of the basic fundamental research to determine the nature and prevalence of hyperaldosteronism in patients with hypertension. Results and Discussion. It was set the frequency of primary hyperaldosteronism in patients with resistant hypertension according to various statistics from 8 to 15 %. For proper treatment of hyperaldosteronism it is necessary the distribution in corrective surgery and not corrective form. Search criteria of hyperaldosteronism are: concierge poorly controlled hypertension combined with arrhythmia, paresthesia, convulsions, heart pain, headache; hypertension, resistant to antihypertensive therapy for at least three drugs; combination of hypertension with hypopotassiumemia; hypertension in young children, especially under 20 years; hypertension and a family history of early hypertension; hyperaldosteronism in cases of direct family relatives. Conclusions. Hyperaldosteronism is a complex syndrome, one manifestation of which is resistant hypertension. In 15 % of patients with hypertension is the cause of hyperaldosteronism. In such cases, surgical treatment, removal of aldosteroma is the only effective treatment for hypertension.