The impact of growth differentiation factor 15 on the risk of cardiovascular diseases: two-sample Mendelian randomization study

The impact of growth differentiation factor 15 on the risk of cardiovascular diseases: two-sample Mendelian randomization study

Abstract Background Growth differentiation factor 15 (GDF-15), a stress responsive cytokine, belongs to transforming growth factor β cytokine superfamily. Some evidence support that it’s involved in inflammation, coagulation, oxidative stress, endothelial dysfunction, and hemostasis. However, it’s s...

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Bibliographic Details
Main Authors: Zhuo Wang, Fangkun Yang, Menghuai Ma, Qinyi Bao, Jinlian Shen, Feiming Ye, Xiaojie Xie
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Cardiovascular Disorders
Subjects:
Cardiovascular diseases
Growth differentiation factor 15
Mendelian randomization
Atrial fibrillation
Cardioembolic stroke
Coronary artery disease
Online Access:http://link.springer.com/article/10.1186/s12872-020-01744-2

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