Structure of transcribing RNA polymerase II-nucleosome complex
Eukaryotic transcription requires passage of RNA polymerase II (Pol II) through chromatin, which is impaired by nucleosomes. Here the authors report the cryo-EM structure of transcribing Pol II engaged with a downstream nucleosome core particle at an overall resolution of 4.4 Å, providing insights i...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2018-12-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-07870-y |