Conformational features of lactate dehydrogenase: temperature effect in presence of small molecules, mathematical model

Conformational features of lactate dehydrogenase: temperature effect in presence of small molecules, mathematical model

The aim of this work was to study the conformational changes of lactate dehydrogenase under the influence of different concentrations of intermediates (pyruvate, oxaloacetate) in the temperature gradient with the  subsequent building of a mathematical model.Materials and methods. Thermolability of l...

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Bibliographic Details
Main Authors: F. N. Gilmiyarova, V. I. Kuzmicheva, N. A. Kolotyeva, M. V. Komarova, E. A. Ryskina, O. A. Gusyakova, D. S. Vinogradova, V. V. Salmin
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2020-10-01
Series:Bûlleten' Sibirskoj Mediciny
Subjects:
lactate dehydrogenase
conformation
differential scanning fluorimetry
oxaloacetate
pyruvate
Online Access:https://bulletin.tomsk.ru/jour/article/view/3586

Internet

https://bulletin.tomsk.ru/jour/article/view/3586

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