Differential Functions of Splicing Factors in Mammary Transformation and Breast Cancer Metastasis

Differential Functions of Splicing Factors in Mammary Transformation and Breast Cancer Metastasis

Summary: Misregulation of alternative splicing is a hallmark of human tumors, yet to what extent and how it contributes to malignancy are only beginning to be unraveled. Here, we define which members of the splicing factor SR and SR-like families contribute to breast cancer and uncover differences a...

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Bibliographic Details
Main Authors: SungHee Park, Mattia Brugiolo, Martin Akerman, Shipra Das, Laura Urbanski, Adam Geier, Anil K. Kesarwani, Martin Fan, Nathan Leclair, Kuan-Ting Lin, Leo Hu, Ian Hua, Joshy George, Senthil K. Muthuswamy, Adrian R. Krainer, Olga Anczuków
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719314433

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http://www.sciencedirect.com/science/article/pii/S2211124719314433

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