Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma

Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma

Surface light chain expression is a feature of mature B-cell neoplasms. Light chain restriction in precursor B acute lymphoblastic leukemia is infrequently seen. We report a case of a 28-year-old female with non-FAB L3 morphology blasts and immunophenotypic features showing overlap between a precurs...

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Main Authors: Nikhil Rabade, Asma Bibi, Kiran Ghodke, Nikhil Patkar, Prashant Tembhare, Pratibha Amare, P G Subramanian, Sumeet Gujral
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Burkitt
leukemia
light chain restriction
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=3;spage=410;epage=412;aulast=Rabade
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spelling doaj-f8247c066cfc4786a2fae2db191be1b62020-11-24T23:34:49ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292016-01-0159341041210.4103/0377-4929.188129Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemmaNikhil RabadeAsma BibiKiran GhodkeNikhil PatkarPrashant TembharePratibha AmareP G SubramanianSumeet GujralSurface light chain expression is a feature of mature B-cell neoplasms. Light chain restriction in precursor B acute lymphoblastic leukemia is infrequently seen. We report a case of a 28-year-old female with non-FAB L3 morphology blasts and immunophenotypic features showing overlap between a precursor and mature B-cell neoplasm.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=3;spage=410;epage=412;aulast=RabadeBurkittleukemialight chain restriction
collection DOAJ
language English
format Article
sources DOAJ
author Nikhil Rabade
Asma Bibi
Kiran Ghodke
Nikhil Patkar
Prashant Tembhare
Pratibha Amare
P G Subramanian
Sumeet Gujral
spellingShingle Nikhil Rabade
Asma Bibi
Kiran Ghodke
Nikhil Patkar
Prashant Tembhare
Pratibha Amare
P G Subramanian
Sumeet Gujral
Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma
Indian Journal of Pathology and Microbiology
Burkitt
leukemia
light chain restriction
author_facet Nikhil Rabade
Asma Bibi
Kiran Ghodke
Nikhil Patkar
Prashant Tembhare
Pratibha Amare
P G Subramanian
Sumeet Gujral
author_sort Nikhil Rabade
title Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma
title_short Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma
title_full Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma
title_fullStr Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma
title_full_unstemmed Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma
title_sort lymphoblastic leukemia with surface light chain restriction: a diagnostic dilemma
publisher Wolters Kluwer Medknow Publications
series Indian Journal of Pathology and Microbiology
issn 0377-4929
publishDate 2016-01-01
description Surface light chain expression is a feature of mature B-cell neoplasms. Light chain restriction in precursor B acute lymphoblastic leukemia is infrequently seen. We report a case of a 28-year-old female with non-FAB L3 morphology blasts and immunophenotypic features showing overlap between a precursor and mature B-cell neoplasm.
topic Burkitt
leukemia
light chain restriction
url http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=3;spage=410;epage=412;aulast=Rabade
work_keys_str_mv AT nikhilrabade lymphoblasticleukemiawithsurfacelightchainrestrictionadiagnosticdilemma
AT asmabibi lymphoblasticleukemiawithsurfacelightchainrestrictionadiagnosticdilemma
AT kiranghodke lymphoblasticleukemiawithsurfacelightchainrestrictionadiagnosticdilemma
AT nikhilpatkar lymphoblasticleukemiawithsurfacelightchainrestrictionadiagnosticdilemma
AT prashanttembhare lymphoblasticleukemiawithsurfacelightchainrestrictionadiagnosticdilemma
AT pratibhaamare lymphoblasticleukemiawithsurfacelightchainrestrictionadiagnosticdilemma
AT pgsubramanian lymphoblasticleukemiawithsurfacelightchainrestrictionadiagnosticdilemma
AT sumeetgujral lymphoblasticleukemiawithsurfacelightchainrestrictionadiagnosticdilemma
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