Development and validation of a prediction model for tocilizumab failure in hospitalized patients with SARS-CoV-2 infection.

<h4>Background</h4>The aim of this secondary analysis of the TESEO cohort is to identify, early in the course of treatment with tocilizumab, factors associated with the risk of progressing to mechanical ventilation and death and develop a risk score to estimate the risk of this outcome a...

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Main Authors: Cristina Mussini, Alessandro Cozzi-Lepri, Marianna Menozzi, Marianna Meschiari, Erica Franceschini, Jovana Milic, Lucio Brugioni, Antonello Pietrangelo, Massimo Girardis, Andrea Cossarizza, Roberto Tonelli, Enrico Clini, Marco Massari, Michele Bartoletti, Anna Ferrari, Anna Maria Cattelan, Paola Zuccalà, Miriam Lichtner, Roberto Rossotti, Enrico Girardi, Emanuele Nicastri, Massimo Puoti, Andrea Antinori, Pierluigi Viale, Giovanni Guaraldi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0247275