Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin

Multi-drug resistant pathogens remain a serious public health threat. Here, Sun and colleagues identify a role for auranofin, which is normally used as a drug for rheumatoid arthritis, for reversing antibiotic resistance to carbapenem and colistin.

Bibliographic Details
Main Authors: Hongzhe Sun, Qi Zhang, Runming Wang, Haibo Wang, Yuen-Ting Wong, Minji Wang, Quan Hao, Aixin Yan, Richard Yi-Tsun Kao, Pak-Leung Ho, Hongyan Li
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18939-y