KCTD19 and its associated protein ZFP541 are independently essential for meiosis in male mice.
Meiosis is a cell division process with complex chromosome events where various molecules must work in tandem. To find meiosis-related genes, we screened evolutionarily conserved and reproductive tract-enriched genes using the CRISPR/Cas9 system and identified potassium channel tetramerization domai...
Main Authors: | Seiya Oura, Takayuki Koyano, Chisato Kodera, Yuki Horisawa-Takada, Makoto Matsuyama, Kei-Ichiro Ishiguro, Masahito Ikawa |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-05-01
|
Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1009412 |
Similar Items
-
Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis
by: Yuki Horisawa-Takada, et al.
Published: (2021-06-01) -
Meiosis-Specific C19orf57/4930432K21Rik/BRME1 Modulates Localization of RAD51 and DMC1 to DSBs in Mouse Meiotic Recombination
by: Kazumasa Takemoto, et al.
Published: (2020-05-01) -
The emerging role of the KCTD proteins in cancer
by: Annapaola Angrisani, et al.
Published: (2021-05-01) -
The RNA binding proteins Zfp3611 and Zfp3612 are essential for early T lymphocyte development
by: Bell, Lewis
Published: (2015) -
Generation and characterization of Kctd15 mutations in zebrafish.
by: Alison Heffer, et al.
Published: (2017-01-01)