The association of a single-nucleotide variant in the microRNA-146a with advanced colorectal cancer prognosis

The association of a single-nucleotide variant in the microRNA-146a with advanced colorectal cancer prognosis

The aim of this study was to evaluate the association of single-nucleotide variant n.60G>C (rs2910164) of microRNA (miR)-146a, related to suppressing of BRCA1/2 DNA repair protein, with the risk and survival of colorectal cancer patients, as well as miR-146a and BRCA1/2 levels and miR binding eff...

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Main Authors: Jéssica Silva dos Santos, Gabriella Lucatto Zunta, Amanda Binatto Negrini, Marina Silva Guinda Ribeiro, Carlos Augusto Real Martinez, Marcelo Lima Ribeiro, Gustavo Jacob Lourenço, Manoela Marques Ortega
Format: Article
Language:English
Published: IOS Press 2020-05-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428320923856

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