Histopathological diagnosis of clot tissues collected by mechanical thrombectomy provides understanding of cerebral infarction pathology in cancer associated thrombosis: A case report

• Main Authors: Toshiaki Bando, Yasushi Ueno, Takahiro Kuroyama, Daisuke Shimo, Kazuyuki Mikami, Shinya Hori, Yuya Tanaka, Osamu Hirai
• Format: Article
• Language: English
• Published: Elsevier 2021-09-01
• Series: Interdisciplinary Neurosurgery
• Subjects: Cancer associated thrombosis; Mechanical thrombectomy; Cardiac metastasis; Histopathological diagnosis
• Online Access: http://www.sciencedirect.com/science/article/pii/S2214751921001237

Endovascular treatment has become a major tool for managing large vessel occlusion, and its applications in cancer associated thrombosis (CAT) is increasing. Histopathological diagnosis of the collected clots aids in understanding the pathology of cerebral infarction, and enables investigation of the relationship between the primary cancer and cerebral infarction if the primary cancer cells are present.We report one lung cancer patient who achieved effective recanalization by mechanical thrombectomy (MT) for acute internal carotid artery (ICA) occlusion. We diagnosed the cause of occlusion as cardiac metastasis from lung cancer based on transthoracic echocardiography and histopathological diagnosis of collected clots.In MT for large vessel occlusion induced by CAT, histopathological diagnosis of the collected clots is useful for understanding the pathology of cerebral infarction.