A simple approach for COnsumption and RElease (CORE) analysis of metabolic activity in single mammalian embryos.

Non-invasive assay of the consumption and release of metabolites by individual human embryos could allow selection at the cleavage stage of development and facilitate Single Embryo Transfer in clinical IVF but will require simple, high throughput, sensitive methods applicable to small volume samples...

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Bibliographic Details
Main Authors: Fabrice Guerif, Paul McKeegan, Henry J Leese, Roger G Sturmey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3744531?pdf=render