Hibiscus sabdariffa Leaf Extract Inhibits Human Prostate Cancer Cell Invasion via Down-Regulation of Akt/NF-kB/MMP-9 Pathway

Hibiscus sabdariffa Leaf Extract Inhibits Human Prostate Cancer Cell Invasion via Down-Regulation of Akt/NF-kB/MMP-9 Pathway

Hibiscus sabdariffa leaf has been previously shown to possess hypoglycemic, hypolipidemic, and antioxidant effects, and induce tumor cell apoptosis. However, the molecular mechanisms involved in the anticancer activity of H. sabdariffa leaf extract (HLE) are poorly understood. The object of the stud...

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Bibliographic Details
Main Authors: Chun-Tang Chiu, Jing-Hsien Chen, Fen-Pi Chou, Hui-Hsuan Lin
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Nutrients
Subjects:
Hibiscus sabdariffa leaf
metastasis
polyphenols
human prostate cancer
Akt/NF-kB/MMP-9 cascade pathway
Online Access:http://www.mdpi.com/2072-6643/7/7/5065

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