Differential recruitment of pre-mRNA splicing factors to alternatively spliced transcripts in vivo.
Alternative splicing in mammalian cells has been suggested to be largely controlled by combinatorial binding of basal splicing factors to pre-mRNA templates. This model predicts that distinct sets of pre-mRNA splicing factors are associated with alternatively spliced transcripts. However, no experim...
Format: | Article |
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Language: | English |
Published: |
Public Library of Science (PLoS)
2005-11-01
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Series: | PLoS Biology |
Online Access: | http://dx.doi.org/10.1371/journal.pbio.0030374 |