Endoplasmic Reticulum Stress PERK-ATF4-CHOP Pathway Is Associated with Hypothalamic Neuronal Injury in Different Durations of Stress in Rats

Endoplasmic Reticulum Stress PERK-ATF4-CHOP Pathway Is Associated with Hypothalamic Neuronal Injury in Different Durations of Stress in Rats

The hypothalamus, which is the initial part of the hypothalamic-pituitary-adrenal (HPA) axis, plays a critical role in regulating stress in the central nervous system. The present study aimed to determine whether endoplasmic reticulum stress in hypothalamic neurons is differentially stimulated by va...

Full description

Bibliographic Details
Main Authors: Shanyong Yi, Weibo Shi, He Wang, Chunling Ma, Xiaojing Zhang, Songjun Wang, Bin Cong, Yingmin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-03-01
Series:Frontiers in Neuroscience
Subjects:
hypothalamus
HPA axis
glucocorticoid
stress
PERK-ATF4-CHOP pathway
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00152/full

Similar Items

Similar Items