Interaction Toxicity Study between P-glycoprotein Inhibitor (Captopril) and Inducer (Spironolactone) with Their Substrate (Lovastatin) in Male Rats

An interaction toxicity study was performed to evaluate and compare the effect of P-glycoprotein (P-gp) inhibitor (captopril) and inducer (spironolactone) on their common substrate (lovastatin) that were done by comparing LD50 of the acute study with their chronic form then with those combined ther...

Full description

Bibliographic Details
Main Authors: Mohammed A. Aboktifa, Duraid A. Abbas
Format: Article
Language:English
Published: University of Baghdad, College of Veterinary Medicine 2020-12-01
Series:The Iraqi Journal of Veterinary Medicine
Subjects:
Online Access:https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1032