Interaction Toxicity Study between P-glycoprotein Inhibitor (Captopril) and Inducer (Spironolactone) with Their Substrate (Lovastatin) in Male Rats
An interaction toxicity study was performed to evaluate and compare the effect of P-glycoprotein (P-gp) inhibitor (captopril) and inducer (spironolactone) on their common substrate (lovastatin) that were done by comparing LD50 of the acute study with their chronic form then with those combined ther...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
University of Baghdad, College of Veterinary Medicine
2020-12-01
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Series: | The Iraqi Journal of Veterinary Medicine |
Subjects: | |
Online Access: | https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1032 |