Distinct Dysfunctional States of Circulating Innate-Like T Cells in Metabolic Disease

Distinct Dysfunctional States of Circulating Innate-Like T Cells in Metabolic Disease

The immune system plays a significant role in controlling systemic metabolism. Innate-like T (ILT) cells in particular, such as mucosal-associated invariant T (MAIT) cells, invariant natural killer T (iNKT) cells and γδ T cell receptor expressing cells, have been reported to promote metabolic homeos...

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Bibliographic Details
Main Authors: Yanyan Li, Katherine Woods, Amber Parry-Strong, Regan J. Anderson, Celina Capistrano, Aurelie Gestin, Gavin F. Painter, Ian F. Hermans, Jeremy Krebs, Olivier Gasser
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
MAIT cells
iNKT cells
Vδ2+ T cells
obesity
type 2 diabetes
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00448/full

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