Deducing the kinetics of protein synthesis in vivo from the transition rates measured in vitro.

The molecular machinery of life relies on complex multistep processes that involve numerous individual transitions, such as molecular association and dissociation steps, chemical reactions, and mechanical movements. The corresponding transition rates can be typically measured in vitro but not in viv...

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Bibliographic Details
Main Authors: Sophia Rudorf, Michael Thommen, Marina V Rodnina, Reinhard Lipowsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4214572?pdf=render