Novel diabetic mouse models as tools for investigating diabetic retinopathy.

Novel diabetic mouse models as tools for investigating diabetic retinopathy.

Mouse models possessing green fluorescent protein (GFP) and/or human aldose reductase (hAR) in vascular tissues have been established and crossed with naturally diabetic Akita mice to produce new diabetic mouse models.Colonies of transgenic C57BL mice expressing GFP (SMAA-GFP), hAR (SMAA-hAR) or bot...

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Bibliographic Details
Main Authors: Peter F Kador, Peng Zhang, Jun Makita, Zifeng Zhang, Changmei Guo, James Randazzo, Hiroyoshi Kawada, Neena Haider, Karen Blessing
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3520987?pdf=render

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