Resveratrol and Resveratrol-Aspirin Hybrid Compounds as Potent Intestinal Anti-Inflammatory and Anti-Tumor Drugs

Resveratrol and Resveratrol-Aspirin Hybrid Compounds as Potent Intestinal Anti-Inflammatory and Anti-Tumor Drugs

Resveratrol (3,4,5-Trihydroxy-trans-stilbene) is a naturally occurring polyphenol that exhibits beneficial pleiotropic health effects. It is one of the most promising natural molecules in the prevention and treatment of chronic diseases and autoimmune disorders. One of the key limitations in the cli...

Full description

Bibliographic Details
Main Authors:	Mohamed Salla, Vrajesh Pandya, Khushwant S. Bhullar, Evan Kerek, Yoke Fuan Wong, Robyn Losch, Joe Ou, Fahad S. Aldawsari, Carlos Velazquez-Martinez, Aducio Thiesen, Jason R. B. Dyck, Basil P. Hubbard, Shairaz Baksh
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Series:	Molecules
Subjects:	resveratrol cancer inflammation NFκB AMPK sirtuin
Online Access:	https://www.mdpi.com/1420-3049/25/17/3849

Similar Items

Wine Resveratrol: From the Ground Up
by: Luigi Bavaresco, et al.
Published: (2016-04-01)

The Role of Resveratrol in Mammalian Reproduction
by: Rolando Pasquariello, et al.
Published: (2020-10-01)

Le resvératrol et l’aspirine éliminent les cellules tétraploïdes pour la chimioprévention du cancer
by: Lissa, Delphine
Published: (2014)

Resveratrol and Vascular Function
by: Huige Li, et al.
Published: (2019-04-01)

Preconception resveratrol intake against infertility: Friend or foe?
by: Asako Ochiai, et al.
Published: (2020-04-01)

Radioprotective and Antioxidant Effect of Resveratrol in Hippocampus by Activating Sirt1
by: Jianguo Li, et al.
Published: (2014-04-01)

Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol
by: Mahadevan Lakshminarasimhan, et al.
Published: (2013-05-01)

Combination of Berberine with Resveratrol Improves the Lipid-Lowering Efficacy
by: Xiaofei Zhu, et al.
Published: (2018-12-01)

Beneficial effect of resveratrol on phenotypic features and activity of osteoarthritic osteoblasts
by: Élie Abed, et al.
Published: (2017-06-01)

Clinical effects of resveratrol (review of the literature)
by: Yu B Uspenskaya
Published: (2014-10-01)

Resveratrol Induces Expression of Metabolic and Antioxidant Machinery and Protects Tilapia under Cold Stress
by: Min-Chen Wang, et al.
Published: (2020-05-01)

Enhancing the Delivery of Resveratrol in Humans: If Low Bioavailability is the Problem, What is the Solution?
by: James M. Smoliga, et al.
Published: (2014-10-01)

Hepatic Proteomic Changes and Sirt1/AMPK Signaling Activation by Oxymatrine Treatment in Rats With Non-alcoholic Steatosis
by: Hong Xu, et al.
Published: (2020-03-01)

Resveratrol Pretreatment Ameliorates Concanavalin A-Induced Advanced Renal Glomerulosclerosis in Aged Mice through Upregulation of Sirtuin 1-Mediated Klotho Expression
by: Chin-Chang Chen, et al.
Published: (2020-09-01)

Involvement of 5′AMP-Activated Protein Kinase (AMPK) in the Effects of Resveratrol on Liver Steatosis
by: Jenifer Trepiana, et al.
Published: (2018-11-01)

Improving the post-thaw quality of rooster semen using the extender supplemented with resveratrol
by: Fereshteh Sadat Rezaie, et al.
Published: (2021-09-01)

Resveratrol inhibits parathyroid hormone-induced apoptosis in human aortic smooth muscle cells by upregulating sirtuin 1
by: Yingjie Liu, et al.
Published: (2019-01-01)

Resveratrol, Metabolic Dysregulation, and Alzheimer’s Disease: Considerations for Neurogenerative Disease
by: Alex J. T. Yang, et al.
Published: (2021-04-01)

SIRT3 Acts as a Positive Autophagy Regulator to Promote Lipid Mobilization in Adipocytes via Activating AMPK
by: Tian Zhang, et al.
Published: (2020-01-01)

Inhibitory effects of resveratrol on hypoxia-induced inflammation in 3T3-L1 adipocytes and macrophages
by: Karina B. Cullberg, et al.
Published: (2014-03-01)

Potential Involvement of Peripheral Leptin/STAT3 Signaling in the Effects of Resveratrol and Its Metabolites on Reducing Body Fat Accumulation
by: Andrea Ardid-Ruiz, et al.
Published: (2018-11-01)

YAP Inhibition by Resveratrol via Activation of AMPK Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine
by: Zhengdong Jiang, et al.
Published: (2016-09-01)

Resveratrol Modulates Apoptosis and Autophagy Induced by High Glucose and Palmitate in Cardiac Cells
by: Kui Xu, et al.
Published: (2018-04-01)

Depigmenting Effect of Resveratrol Is Dependent on FOXO3a Activation without SIRT1 Activation
by: Soon-Hyo Kwon, et al.
Published: (2017-06-01)

Resveratrol Protects Osteoblasts Against Dexamethasone-Induced Cytotoxicity Through Activation of AMP-Activated Protein Kinase
by: Wang L, et al.
Published: (2020-10-01)

The effect of aerobic exercise along with resveratrol supplementation on myocardial AMPK and MAFbx gene expression of diabetic rats
by: Bentollhoda Esmailee, et al.
Published: (2020-06-01)

Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy
by: He Tian, et al.
Published: (2021-01-01)

Resveratrol Prevents GLUT3 Up-Regulation Induced by Middle Cerebral Artery Occlusion
by: Germán Fernando Gutiérrez Aguilar, et al.
Published: (2020-09-01)

Resveratrol induces autophagy-dependent apoptosis in HL-60 cells
by: Yingying Fan, et al.
Published: (2018-05-01)

Resveratrol Prevented Lipopolysaccharide-Induced Endothelial Dysfunction in Rat Thoracic Aorta Through Increased eNOS Expression
by: Seda Sultan Uğurel, et al.
Published: (2016-04-01)

Sirtuin as the target of anti-cancer therapy
by: Marzena Baran, et al.
Published: (2020-08-01)

Satellite Cells and Markers of Muscle Regeneration during Unloading and Reloading: Effects of Treatment with Resveratrol and Curcumin
by: Laura Mañas-García, et al.
Published: (2020-06-01)

Effects of resveratrol on Th17 cell-related immune responses under tacrolimus-based immunosuppression
by: Kyoung Chan Doh, et al.
Published: (2019-03-01)

Anti-Inflammatory Action and Mechanisms of Resveratrol
by: Tiantian Meng, et al.
Published: (2021-01-01)

Resveratrol: Anti-Obesity Mechanisms of Action
by: Leixuri Aguirre, et al.
Published: (2014-11-01)

Curcuminoids and resveratrol as anti-Alzheimer agents
by: Oliver B. Villaflores, et al.
Published: (2012-12-01)

Resveratrol Ameliorates Microcystin-LR-Induced Testis Germ Cell Apoptosis in Rats via SIRT1 Signaling Pathway Activation
by: Haohao Liu, et al.
Published: (2018-06-01)

Resveratrol promotes axonal regeneration via PI3K/Akt pathway in rats after intracerebral hemorrhage
by: WANG Guanyu, et al.
Published: (2019-08-01)

Effects of resveratrol on proliferation of retinal vascular endothelial cells and acetylated HMGB1 in high glucose environment
by: Yan Wei, et al.
Published: (2015-12-01)

Curcumin and Resveratrol Improve Muscle Function and Structure through Attenuation of Proteolytic Markers in Experimental Cancer-Induced Cachexia
by: Antonio Penedo-Vázquez, et al.
Published: (2021-08-01)