Intercellular communication between artificial cells by allosteric amplification of a molecular signal
The principles of intercellular communication in multicellular organisms can be explored using artificial cells. Here, the authors report on giant vesicles which can recognize diffused chemical signals and amplify the signal by synthetic enzymatic cascades to allow signal propagation over long dista...
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2020-04-01
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Online Access: | https://doi.org/10.1038/s41467-020-15482-8 |
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doaj-f78319b741ce4529a4b75adb7a84d8922021-05-11T08:01:27ZengNature Publishing GroupNature Communications2041-17232020-04-0111111010.1038/s41467-020-15482-8Intercellular communication between artificial cells by allosteric amplification of a molecular signalBastiaan C. Buddingh’0Janneke Elzinga1Jan C. M. van Hest2Department of Chemical Engineering and Chemistry, Eindhoven University of TechnologyRadboud UniversityDepartment of Chemical Engineering and Chemistry, Eindhoven University of TechnologyThe principles of intercellular communication in multicellular organisms can be explored using artificial cells. Here, the authors report on giant vesicles which can recognize diffused chemical signals and amplify the signal by synthetic enzymatic cascades to allow signal propagation over long distances.https://doi.org/10.1038/s41467-020-15482-8 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bastiaan C. Buddingh’ Janneke Elzinga Jan C. M. van Hest |
spellingShingle |
Bastiaan C. Buddingh’ Janneke Elzinga Jan C. M. van Hest Intercellular communication between artificial cells by allosteric amplification of a molecular signal Nature Communications |
author_facet |
Bastiaan C. Buddingh’ Janneke Elzinga Jan C. M. van Hest |
author_sort |
Bastiaan C. Buddingh’ |
title |
Intercellular communication between artificial cells by allosteric amplification of a molecular signal |
title_short |
Intercellular communication between artificial cells by allosteric amplification of a molecular signal |
title_full |
Intercellular communication between artificial cells by allosteric amplification of a molecular signal |
title_fullStr |
Intercellular communication between artificial cells by allosteric amplification of a molecular signal |
title_full_unstemmed |
Intercellular communication between artificial cells by allosteric amplification of a molecular signal |
title_sort |
intercellular communication between artificial cells by allosteric amplification of a molecular signal |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2020-04-01 |
description |
The principles of intercellular communication in multicellular organisms can be explored using artificial cells. Here, the authors report on giant vesicles which can recognize diffused chemical signals and amplify the signal by synthetic enzymatic cascades to allow signal propagation over long distances. |
url |
https://doi.org/10.1038/s41467-020-15482-8 |
work_keys_str_mv |
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1721451225010929664 |