Intercellular communication between artificial cells by allosteric amplification of a molecular signal

The principles of intercellular communication in multicellular organisms can be explored using artificial cells. Here, the authors report on giant vesicles which can recognize diffused chemical signals and amplify the signal by synthetic enzymatic cascades to allow signal propagation over long dista...

Full description

Bibliographic Details
Main Authors: Bastiaan C. Buddingh’, Janneke Elzinga, Jan C. M. van Hest
Format: Article
Language:English
Published: Nature Publishing Group 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15482-8
id doaj-f78319b741ce4529a4b75adb7a84d892
record_format Article
spelling doaj-f78319b741ce4529a4b75adb7a84d8922021-05-11T08:01:27ZengNature Publishing GroupNature Communications2041-17232020-04-0111111010.1038/s41467-020-15482-8Intercellular communication between artificial cells by allosteric amplification of a molecular signalBastiaan C. Buddingh’0Janneke Elzinga1Jan C. M. van Hest2Department of Chemical Engineering and Chemistry, Eindhoven University of TechnologyRadboud UniversityDepartment of Chemical Engineering and Chemistry, Eindhoven University of TechnologyThe principles of intercellular communication in multicellular organisms can be explored using artificial cells. Here, the authors report on giant vesicles which can recognize diffused chemical signals and amplify the signal by synthetic enzymatic cascades to allow signal propagation over long distances.https://doi.org/10.1038/s41467-020-15482-8
collection DOAJ
language English
format Article
sources DOAJ
author Bastiaan C. Buddingh’
Janneke Elzinga
Jan C. M. van Hest
spellingShingle Bastiaan C. Buddingh’
Janneke Elzinga
Jan C. M. van Hest
Intercellular communication between artificial cells by allosteric amplification of a molecular signal
Nature Communications
author_facet Bastiaan C. Buddingh’
Janneke Elzinga
Jan C. M. van Hest
author_sort Bastiaan C. Buddingh’
title Intercellular communication between artificial cells by allosteric amplification of a molecular signal
title_short Intercellular communication between artificial cells by allosteric amplification of a molecular signal
title_full Intercellular communication between artificial cells by allosteric amplification of a molecular signal
title_fullStr Intercellular communication between artificial cells by allosteric amplification of a molecular signal
title_full_unstemmed Intercellular communication between artificial cells by allosteric amplification of a molecular signal
title_sort intercellular communication between artificial cells by allosteric amplification of a molecular signal
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-04-01
description The principles of intercellular communication in multicellular organisms can be explored using artificial cells. Here, the authors report on giant vesicles which can recognize diffused chemical signals and amplify the signal by synthetic enzymatic cascades to allow signal propagation over long distances.
url https://doi.org/10.1038/s41467-020-15482-8
work_keys_str_mv AT bastiaancbuddingh intercellularcommunicationbetweenartificialcellsbyallostericamplificationofamolecularsignal
AT jannekeelzinga intercellularcommunicationbetweenartificialcellsbyallostericamplificationofamolecularsignal
AT jancmvanhest intercellularcommunicationbetweenartificialcellsbyallostericamplificationofamolecularsignal
_version_ 1721451225010929664