Animal Models for COVID-19: Hamsters, Mouse, Ferret, Mink, Tree Shrew, and Non-human Primates

Animal Models for COVID-19: Hamsters, Mouse, Ferret, Mink, Tree Shrew, and Non-human Primates

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus causing acute respiratory tract infection in humans. The virus has the characteristics of rapid transmission, long incubation period and strong pathogenicity, and has spread all over the world. Therefore, it is of gr...

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Bibliographic Details
Main Authors: Shuyu Shou, Menghui Liu, Yang Yang, Ning Kang, Yingying Song, Dan Tan, Nannan Liu, Feifei Wang, Jing Liu, Youhua Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Microbiology
Subjects:
COVID-19
SARS-CoV-2
ACE2 (angiotensin converting enzyme 2)
animal model
pathogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.626553/full
Description
Summary:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus causing acute respiratory tract infection in humans. The virus has the characteristics of rapid transmission, long incubation period and strong pathogenicity, and has spread all over the world. Therefore, it is of great significance to select appropriate animal models for antiviral drug development and therapeutic effect evaluation. Here, we review and compare the current animal models of SARS-CoV-2.
ISSN:1664-302X

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