Expression of LIM kinase 1 is associated with reversible G1/S phase arrest, chromosomal instability and prostate cancer

Expression of LIM kinase 1 is associated with reversible G1/S phase arrest, chromosomal instability and prostate cancer

<p>Abstract</p> <p>Background</p> <p>LIM kinase 1 (LIMK1), a LIM domain containing serine/threonine kinase, modulates actin dynamics through inactivation of the actin depolymerizing protein cofilin. Recent studies have indicated an important role of LIMK1 in growth and...

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Bibliographic Details
Main Authors: Grizzle William E, Ghosh Debashis, Jhala Darshana, Davila Monica, Chakrabarti Ratna
Format: Article
Language:English
Published: BMC 2007-06-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/6/1/40

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