The Role of Dendritic Cells in S. pneumoniae Transport to Follicular Dendritic Cells

Affinity-mature B cells require cognate antigen, retained by follicular dendritic cells (FDCs), for clonal selection within germinal centers. Studies on how FDCs in lymphoid tissues acquire antigen have relied primarily on model protein antigens. To examine delivery of intact bacteria to FDCs, we us...

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Bibliographic Details
Main Authors: Balthasar A. Heesters, Michael C. Carroll
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716311305